Brd7 antibody
WebBRD7 acts both as coactivator and as corepressor. For example, it activates the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. In addition, it is … WebImmunofluorescent analysis of BRD7 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and …
Brd7 antibody
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WebNov 28, 2024 · VZ185 is an effective and highly selective degrader of BRD7/9 proteins in cells. In vitro PK data further shows high stabilities of VZ185 in both plasma and microsomes from both human and mouse species, as well as high aqueous kinetic solubility (up to ∼100 μM). It also shows preference for BRD9 as compared to BRD7 (BRD9-DC 50 = 4 nM; … WebBRD7 antibody (ABIN1963609). Validated for ELISA, WB. Tested in Human, Mouse. Order online. English ... Comparison List Basket Phone: +1 877 302 8632 Fax: +1 888 205 9894 (Toll-free) E-Mail: [email protected]. Home Antibodies ELISA Kits Primary Antibodies. Monoclonal Antibodies; Polyclonal Antibodies; Recombinant Antibodies ...
WebBRD7 acts both as coactivator and as corepressor. For example, it activates the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. In addition, it is required for TP53-mediated cell-cycle arrest in response to oncogene activation. WebMar 6, 2024 · BRD7 Antibody (B-8) is a mouse monoclonal IgG 2a κ BRD7 antibody, cited in 12 publications, provided at 200 µg/ml. raised against amino acids 397-473 …
WebBRD7 acts both as coactivator and as corepressor. For example, it activates the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. In addition, it is required for TP53-mediated cell-cycle arrest in response to oncogene activation. WebExhibits selectivity for BRD7/9 degradation over other bromodomain-containing proteins and other BAF/PBAF subunits. Displays cytotoxicity towards EOL-1 and A-204 cancer cell lines. Negative control cis VZ 185 (Cat. No. 6939) also …
WebAnti-BRD7 antibodies are offered by a number of suppliers. This target gene encodes the protein 'bromodomain containing 7' in humans and may also be known as BP75, CELTIX1, NAG4, bromodomain-containing protein 7, and 75 kDa bromodomain protein. Structurally, the protein is reported to be 74.1 kilodaltons in mass.
WebThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - … chelsea vs everton predicted lineupWebBiological Activity. VZ185 (VZ-185) is a potent, fast and selective, VHL-based dual degrader probe (PROTAC) of BRD9 and BRD7 with DC50 of 1.8 and 4.5 nM, respectively. VZ185 induces strong and rapid degradation of of BRD9, BRD7 in a time- and dose-dependent manner after treatment of RI-1 cells, also shows a DC50 between 2-8 nM for BRD9 in a ... flexsteel thornton leather sofa priceWebBRD7 Antibody (PA5-96105) in WB. Western Blot analysis of BRD7 in extracts of various cell lines using BRD7 Polyclonal Antibody ( Product # PA5-96105) at a dilution of 1:1000. A HRP Goat Anti-Rabbit IgG (H+L) secondary antibody was used at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. chelsea vs fanpassWebBromodomain-containing protein 7 was identified in a two-hybrid screen as an interactor of interferon regulatory factor-2 (IRF-2) and called CELTIX1. BRD7 was also identified as a binding partner of disheveled-1 (Dvl-1) … flexsteel theo recliner for saleWebRabbit monoclonal [EPR24342-71] to BRD7 Suitable for: WB, IHC-P Reacts with: Human Related conjugates and formulations Carrier Free You may also be interested in Primary … flexsteel thornton queen sleeper sofaWebFeb 16, 2016 · BRD7 was first identified as a novel bromodomain gene with a single bromodomain related to multiple types of cancers 12, 13. As a tumor suppressor gene, BRD7 inhibits cell growth and cell cycle... chelsea vs everton streamingWebAntibodies Primary Antibodies and ImmunoCruz® Conjugates Cell Cycle Proteins BRD7 Antibodies BRD7 Antibodies Santa Cruz Biotechnology, Inc. offers a broad range of BRD7 antibodies. Select BRD7 antibodies from monoclonal antibodies listed below. View detailed BRD7 antibody specifications by linking to the specific product blocks. flexsteel thornton chair