Cytoskeleton-associated protein 4
WebSep 19, 2024 · Cytoskeleton-associated protein 4 (CKAP4; also known as p63, CLIMP-63, or ERGIC-63) is a 63 kDa, reversibly palmitoylated and phosphorylated, type II transmembrane (TM) protein, originally identified as a resident of the endoplasmic reticulum (ER)/Golgi intermediate compartment (ERGIC). CKAP4 as a receptor of APF plays an important role in mediating bladder carcinoma cells proliferation. Following CKAP4 knockdown, the inhibition effect of APF on T24 cell proliferation was eliminated, indicating the important role of the receptor in mediating the antiproliferation activity of APF in bladder cancer … See more Our group investigated the relationship between CKAP4/DHHC2 expression and prognosis in 416 patients with hepatocellular carcinoma (HCC) (Li et al., 2014b) (Table 2). … See more Previous studies reported that CKAP4 as an ER enriched protein could be secreted by exosomes of ovarian and colon cancer cells and detected as an exosomal protein in urine (Gonzales et al., 2009; Demory Beckler et al., 2013; … See more Although plentiful researches focused on the relationship between CKAP4 and cancer, there were also studies that showed that CKAP4 played an important role in noncancers. … See more Sufficient studies have confirmed that CKAP4 correlated with various cancers’ progress and prognosis. The formation of the xenograft tumors derived from CKAP4-depleted cells, including lung cancer cells (Kimura et al., 2016), … See more
Cytoskeleton-associated protein 4
Did you know?
WebIn cell biology, microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton. MAPs are integral to the stability of the cell and its internal structures and the transport of components within the cell. ... "XMAP215: a key component of the dynamic microtubule cytoskeleton". Trends Cell ... WebFeb 25, 2024 · They applied it for the first time to the intestine and identified regenerating islet-derived protein 4 ( Reg4) as a novel marker for enteroendocrine cells, a rare population of hormone-producing intestinal cells [ 32 ]. Regenerative properties of the adult mammalian heart are insufficient to repair the heart post-ischemic injury.
WebAug 7, 2024 · Regenerative medicine represented by stem cell technology has become one of the pillar medical technologies for human disease treatment. Cytoskeleton plays important roles in maintaining cell morphology, bearing external forces, and maintaining the effectiveness of cell internal structure, among which cytoskeleton related proteins are … WebCytoskeleton-associated protein 4 (CKAP4) is also known as p63 and cytoskeleton-linking membrane protein 63kDa (CLIMP-63). It was first described as a palmitoylated single-pass transmembrane receptor that localized to the rough endoplasmic reticulum as well as the cell membrane.
WebOct 25, 2010 · Deep sequencing of mutant DNA revealed a mutation located in an intron of the Mtap2 gene, encoding microtubule-associated protein 2, and levels of Mtap2 transcript were reduced in mutant testes. ... Together, these and other as yet unknown regulators bring about progressive changes in the nucleus and cytoskeleton, including desynapsis, ... WebFeb 5, 2024 · Cytoskeleton-associated protein 4 (CKAP4) is located in the rough endoplasmic reticulum (ER) and plays an important role in stabilizing the structure of ER. …
WebWhat Is the Cytoskeleton Made Of? The cytoskeleton of eukaryotic cells is made of filamentous proteins, and it provides mechanical support to the cell and its cytoplasmic constituents. All...
WebApr 7, 2015 · cytoskeleton-linking membrane protein (CLIMP-63)/ cytoskeleton-associated protein 4 (CKAP4), palmitoyl-acyltransferase 2 (has a DHHC motif) [DHHC2], endoplasmic reticulum (ER) cytoskeleton anchor, nuclear translocation, palmitoylation, plasma membrane receptor, rough endoplasmic reticulum (RER) c++ std string wstring 変換WebCytoskeleton-associated protein 4 is a novel serodiagnostic marker for esophageal squamous-cell carcinoma. Background: Recent years have witnessed significant … c# struct by refWebActivity-regulated cytoskeleton-associated protein is a plasticity protein that in humans is encoded by the ARC gene. It was first characterized in 1995. [5] [6] ARC is a member of the immediate-early gene (IEG) family, a rapidly activated class of genes functionally defined by their ability to be transcribed in the presence of protein ... c++ string to time_pointWebAppropriate cytoskeletal organization is essential for vascular smooth muscle cell (VSMC) conditions such as hypertension. This study identifies FXR1 … c# thread countWebMar 21, 2024 · Cytoskeleton-associated protein 4 (CKAP4) promotes malignant progression of human gliomas through inhibition of the Hippo signaling pathway. … c++ static table initWebCytoskeleton-associated protein 4 (CKAP4) is a non-glycosylated type II transmembrane protein that serves as a cell surface-activated receptor. It is expressed primarily in … c. sharkey enterprises incWebMay 17, 2024 · CKAP4 (cytoskeleton‐associated protein 4) is a DKK1 binding protein expressed on the surface of cells, with DKK1/CKAP4 promoting pancreatic cancer and lung cancer . DKK1 is considered a factor that can modulate the β‐catenin pathway and stimulate cancer cells or noncancerous proliferation [61, 62]. Zyxin localizes to focal adhesion sites ... c++ tuple int int int