Determing c-myb protein level can isolate
WebUsing this reporter line we demonstrate that subtypes of HSCs can be isolated based upon their respective c-Myb protein expression levels. HSCs expressing low levels of c-Myb … WebAug 1, 1991 · Various alterations of c-Myb itself may determine the lineage of differentiating hematopoietic cells, and the presence of either the normal amino or carboxyl terminus of c -Myb can suppress transformation when fused to v- myb. The protein product of the v-myb oncogene of avian myeloblastosis virus, v-Myb, differs from its normal cellular …
Determing c-myb protein level can isolate
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WebSep 21, 2010 · The dotted line indicates the position of the nonsense mutation that is predicted to cause truncation of the C-MYB protein in the medaka mutant. C-MYB. C-MYB was discovered as the cellular proto-oncogene from which the V-MYB oncogene arose via retroviral transduction in the avian myeloblastosis virus . This virus causes rapidly fatal ... WebOct 14, 2015 · miR-150 preferentially targets c-Myb protein levels in C2C12 myoblasts. ... Sakamoto, H. et al. Determining C-Myb Protein Levels can Isolate Functional Hematopoietic Stem Cell Subtypes. Stem Cells ...
WebUsing this reporter line we demonstrate that subtypes of HSCs can be isolated based upon their respective c-Myb protein expression levels. HSCs expressing low levels of c-Myb … WebOct 3, 2011 · The Myb oncogene family was discovered because of the retroviral transduction of the chicken cellular myb protooncogene that generated the avian myeloblastosis virus (1, 2).Both the cellular Myb and viral Myb proteins are present within the nucleus of the cell, bind to specific DNA sequences, and can regulate gene …
WebDetermining c-Myb Protein Levels Can Isolate Functional Hematopoietic Stem Cell Subtypes HIROSHI SAKAMOTO,a NAOKI TAKEDA,b FUMIO ARAI,c KENTARO … WebFeb 1, 2015 · The discrimination of HSC subpopulations based on c-Myb protein levels is not reflected in the levels of c-myb mRNA, there being no more than a 1.3-fold …
WebApr 10, 2024 · SNAREs (soluble N-ethylmaleimide-sensitive-factor attachment protein receptors) are engines for almost all of the membrane fusion and exocytosis events in organism cells. In this study, we identified 84 SNARE genes from banana (Musa acuminata). Gene expression analysis revealed that the expression of MaSNAREs varied a lot in …
WebThe 48-kDa v-Myb protein is truncated relative to the normal 75-kDa c-Myb protein at both its amino and carboxyl termini (Figs. 1 and 2) (Gerondakis and Bishop, 1986; Rosson and Reddy, 1986). In addition, v-Myb contains 10 amino acid substitutions relative to the homologous region of c-Myb (a previously described eleventh substitution was not ... download gotham font family freeWebAlthough c-Myb expression has been reported in the skin, colon, respiratory tract, retina, testes, primary fibroblasts, and endothelial cells, the protein is most readily detected in immature hematopoietic precursors at high levels. These levels of c-Myb decrease as cells progress toward terminal differentiation (17, 27, 54, 63). Alterations in ... download gotham medium italicWebOct 14, 2015 · miR-150 preferentially targets c-Myb protein levels in C2C12 myoblasts. ... Sakamoto, H. et al. Determining C-Myb Protein Levels can Isolate Functional … download gotham light fontWebThe 48-kDa v-Myb protein is truncated relative to the normal 75-kDa c-Myb protein at both its amino and carboxyl termini (Figs. 1 and 2) (Gerondakis and Bishop, 1986; Rosson … download gotham font freeWebTISSUE-SPECIFIC STEM CELLS Determining c-Myb Protein Levels Can Isolate Functional Hematopoietic Stem Cell Subtypes HIROSHI SAKAMOTO,a NAOKI TAKEDA,b FUMIO ARAI,c KENTARO HOSOKAWA,c PALOMA GARCIA,d TOSHIO SUDA,c JON FRAMPTON,d MINETARO OGAWAa,e Key Words. Hematopoietic stem cells • Proto … download gotham medium fontWebOct 14, 2015 · For instance, hematopoietic stem cells differing in c-Myb protein levels more than 2-fold exhibit no more than 1.3-fold difference in c-myb mRNA levels 35. ... Sakamoto H. et al. Determining C-Myb Protein Levels can Isolate Functional Hematopoietic Stem Cell Subtypes. Stem Cells, 10.1002/stem.1855 (2014). download gotham font for windowsWebFeb 1, 2015 · The transcription factor c-Myb was originally identified as a transforming oncoprotein encoded by two avian leukemia viruses. Subsequently, through the generation of mouse models that affect its expression, c-Myb has been shown to be a key regulator of hematopoiesis, including having critical roles in hematopoietic stem cells (HSCs). download gotham font for pc