WebTwo patients (10%) in cohort-2 developed a grade 2 adrenal insufficiency caused by hypophysitis. Grade 3 irAE occurred in three patients (8%) and one patient (4%) in cohort-1 and cohort-2, respectively. ... The combination of neoadjuvant ipilimumab plus nivolumab induced a 2-year RFS-rate of more than 80%; however, at the cost of a high ... WebCaroline Gaudy's 14 research works with 556 citations and 1,436 reads, including: Évaluation de l’efficacité et de la tolérance des anti-PD-1 dans la prise en charge des carcinomes ...
Ipilimumab-induced hypophysitis involving the optic …
WebIpilimumab-induced hypophysitis usually involves the anterior lobe, resulting in central hypothyroidism, central adrenal insufficiency, and hypogonadism. Prolactin levels are … WebAbstract. Ipilimumab is a promising new immunotherapeutic antineoplastic agent with clinical activity in the treatment of metastatic melanoma and renal cell carcinoma. With … open secret documentary full
Caroline Gaudy
WebHypophysitis develops relatively soon after treatment initiation with ipilimumab, typically after 2 or 3 cycles of therapy. Hypophysitis may be diagnosed over a much broader period … WebSep 20, 2024 · Few published cases, mostly referring to ipilimumab, which has been longer used, suggest an association with endocrine immune-related adverse events, such as hypophysitis and thyroid dysfunction [ 8 ]. Only few cases report nivolumab induced-hypophysitis, mostly in patients still undergoing treatment [ 9 ]. WebApr 12, 2024 · Mit dem Anstieg der Immuntherapie steigt auch die Bedeutung der radiologischen Beurteilung häufiger und schwerwiegender immunbedingter Nebenwirkungen. Diese Übersicht geht die häufigsten Befunde durch und gibt Ihnen Bildbeispiele an die Hand, mit denen Sie immuntherapie-assoziierte Befunde von … open secrets ecolab