Phospho-sting-s366

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August undefined, 2024

WebPhospho-STING (Ser366) (E9A9K) Rabbit mAb from Cell Signaling Technology Supplier PageView Company Product Page Product Specs Company Info Reviews Back To Top Biocompare is the leading resource for up-to-date product information, product reviews, and new technologies for life scientists. About Biocompare About Biocompare WebPhosphorylated S366 is a docking site for IRF3 and is essential for the subsequent induction of Interferons (IFNs) ( 7, 8 ). Our previous work demonstrated that IRF3 binds to phosphorylated STING in the late endosomal compartment, where TBK1 phosphorylates and activates IRF3 ( 9 ). Additional proteins regulate the trafficking of STING.

Phospho-STING (Ser366) (D7C3S) Rabbit mAb

WebApr 6, 2024 · Binding of TBK1 to this motif promotes the phosphorylation of S366 in the STING tail 19, which subsequently recruits and promotes the phosphorylation of the transcription factor interferon... WebHTRF phospho-STING (S366) 64STGPEG HTRF total-STING 64NTGPEG HTRF phospho-TBK1 (S172) 64TBKPEG HTRF total-TBK1 64NTBPEG HTRF phospho-IRF3 (S386) 6FRF3PEG HTRF human IFNb 62HIFNBPEG Compounds References 2’3’ cGAMP C161-Biolog c-diAMP C088-Biolog c-diGMP C057-Biolog DMXAA D5817 –Sigma-Aldrich. simple solutions math books

Balancing STING in antimicrobial defense and autoinflammation

WebOct 19, 2024 · Here, we looked for a mechanism that explains how STING-dependent immune signalling is ended. We tracked activated STING (phosphorylated at S366; hereafter pSTING)) (ref. 17) along its intracellular trafficking route by high-resolution confocal and Airyscan microscopy in HeLa cells. WebFeb 7, 2024 · TBK-independent phosphorylation of STING(S366) and its adaptor molecule TICAM2 by phospho-AKT(T308S473) augmented downstream IRF3-dependent IDO1 transcription, which was also dependent on β-catenin. WebPhospho-STING (Ser366) Antibody (PA5-117276) in WB Western blot analysis of extracts of THP-1 cells using Phospho-STING (Ser366) Polyclonal Antibody ( Product # PA5-117276 ). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Product Details ray conniff s wonderful album songs

STING Pathway Expression Identifies NSCLC With an Immune …

Clathrin-associated AP-1 controls termination of STING signalling

WebOct 19, 2024 · Extended Data Fig. 9 Density maps and structural models of the AP-1–pSTING complex. The density maps (grey mesh) of AP-1 and pSTING contoured at 3σ. The protein structures fitted into the density... WebProduct Description. This Cell Signaling Technology antibody is conjugated to Alexa Fluor ® 488 fluorescent dye and tested in-house for direct flow cytometric and immunofluorescent analysis in human cells. The antibody is expected to exhibit the same species cross-reactivity as the unconjugated Phospho-STING (Ser366) (D8K6H) Rabbit mAb #40818. ray conniff the continental discogsWebStimulator of interferon genes (STING, TMEM173, MITA) is a transmembrane adaptor protein that is a critical component of the cellular innate immune response to pathogenic cytoplasmic DNA (1,2). STING is a ubiquitously expressed protein found predominantly in the ER (1). The enzyme cGAMP synthase (cGAS) produces the second messenger cyclic … ray conniff s wonderful album

"WebMay 1, 2024 · (A) Heatmap shows correlation of phospho-STING (Ser_366) protein levels with cGAS and other immune-related proteins in the MD Anderson PROSPECT cohort, … " - Phospho-sting-s366

Phospho-sting-s366

Clathrin-associated AP-1 controls termination of STING signalling

WebPhospho-STING (Ser366) Antibody (PA5-105674) in ICC/IF. Immunofluorescent analysis of Phospho-STING (Ser366) in HepG2 cells … WebThe antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns. Storage: …

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WebPhospho-STING (Ser366) two-plate assay protocol. The two-plate protocol involves culturing cells in a 96-well plate before lysis then transferring lysates to a low volume detection plate (either HTRF 384-lv or 96-lv plate) before adding HTRF Phospho-STING (Ser366) detection reagents. This protocol enables the cells' viability and confluence to ... WebWestern blot - Phospho-STING/TMEM173-S366 Rabbit pAb (AP1223) Western blot analysis of THP-1, using Phospho-STING/TMEM173-S366 …

WebWestern blot - Phospho-STING-S365 Rabbit pAb (AP1199) Western blot analysis of extracts of THP-1 cells, using Phospho-STING-S365 antibody (AP1199) at 1:1000 dilution.THP-1 cells were treated by PMA (80 nM) at 37℃ for overnight. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Web靶标信息. STING is a 379 amino acid containing signaling protein that acts as an important component of innate immune signaling. This signaling protein is able to activate both NF …

WebAnti-Phospho-STING-S365 antibody produced in rabbit; find Sigma-Aldrich-SAB5701942 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich ... Anti-Phospho-TMEM173-S366 antibody produced in rabbit. View Price and Availability. ... Anti-phospho-Smad2/3 (pThr 8) antibody produced in rabbit. affinity ... WebPhospho-TMEM173/STING (Ser366) Antibody Phospho-TMEM173/STING (Ser366) Antibody - #AF7416 (6) (9) WB IHC IF/ICC pElisa Cites 1 /9 Western blot analysis of extracts from UV treated RAW264. View similar products>> Related products Secondary Antibodies Loading Controls Blocking Peptides Cat.#S0018 Cat.#S0006 Cat.#S0008 Cat.#S0001 Cat.#S0013 …

WebJul 22, 2024 · Wu et al. demonstrate that HER2 recruits AKT1 to disrupt the STING signalosome, thereby suppressing damage-induced cellular senescence and STING …

Phospho-STING (Ser366) (D7C3S) Rabbit mAb recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser366 of human STING protein. Background ray conniff talk of the townWebSep 23, 2024 · These findings provide insight into the mechanisms of PARPis in CAR-T cell therapy for RCC and suggest a promising adjuvant therapeutic strategy for CAR-T cell therapy in solid tumors. Supplementary Information The online version contains supplementary material available at 10.1186/s13045-021-01168-1. ray conniff s wonderfulWebThe work by Lehmann et al classified TNBC into six subtypes in 2011. 5 Following this, two studies at our center further identified four transcriptome-based subtypes in TNBC: luminal androgen receptor (LAR), immunomodulatory (IM), basal-like immune-suppressed (BLIS), and mesenchymal-like (MES). 6 7 Furthermore, several reports have also … simple solutions math grade 4 answer keyWebApr 6, 2024 · STING is a transmembrane dimeric protein that is located in the endoplasmic reticulum or in the Golgi apparatus. ... Binding of TBK1 to this motif promotes the … ray conniff the little drummer boyWebPhospho-STING (Ser366) (E9A9K) Rabbit mAb from Cell Signaling Technology Supplier PageView Company Product Page Product Specs Company Info Reviews Back To Top … ray conniff the continentalWebPhospho Sting S366, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 2 PubMed citations. ZERO BIAS - scores, article … ray conniff tammyWeb(19781) Phospho-STING (Ser366) (D7C3S) Rabbit mAb Sign in or register to save this reagent to your favourites Supplier Cell Signaling Technology Host Rabbit Type Primary … ray conniff tea for two